THE VITAMIN B12 AND FOLATE PATHOLOGY INVESTIGATION
THE INVESTIGATION OF ERRORS IN PATHOLOGY TESTS
FOR VITAMIN B12 AND FOLATE DEFICIENCY
BY MEANS OF MEDICAL EXPERIMENTS
THE HOMOCYSTEINE INVESTIGATION
THE HCY EXPERIMENT
Summary
Objectives
Findings
Method
Analysis - CI
Analysis - Pxu
Analysis - Pab
Observations
Lab Performance
Results - Notes
Notes for Charts and Tables
Results - Series 1
CHW Qualitative
CHW Quantitative
Results - Series 1b
HCY Lab Comparison
Conclusions
Diagnostic Utility

The objective of the tHcy experiment was to investigate the quality of total homocysteine assays performed by these laboratories:

  • Sullivan Nicolaides Pathology (SNP)
  • Queensland Health Pathology Service (QHPS)
  • NSW Biochemical Genetics Service at The Children's Hospital Westmead (CHW)
  • Pacific Laboratory Medicine Service (PALMS)
  • Royal Prince Alfred Hospital Pathology (RPAH

This followed the discovery of very significant differences between laboratories during the serum vitamin B12 experiment.

The original serum B12 experiment is described in THE SERUM VITAMIN B12 INVESTIGATION.

 
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