THE VITAMIN B12 AND FOLATE PATHOLOGY INVESTIGATION
THE INVESTIGATION OF ERRORS IN PATHOLOGY TESTS
FOR VITAMIN B12 AND FOLATE DEFICIENCY
BY MEANS OF MEDICAL EXPERIMENTS
THE SERUM VITAMIN B12 INVESTIGATION
THE SERUM B12 EXPERIMENT - A
Summary
Method
Observations
Results - Notes
Results - Assay Quality
Results - Analyte Utility
Serum B12 vs CHW HCY
Conclusions

The important points to note, about response of serum B12, from these SNP results are:

  • Initially borderline low quoted by SNP
  • Increased rapidly after commencing oral B12 on 2 November 2005
  • Fell rapidly to 323 pmol/L, after ceasing oral B12 on 10 February 2006
  • Continued to fall at much slower rate
  • Never fell below SNP normal range
  • Increased rapidly after re-commencing oral B12 on 13 November 2006

The important points to note, about homocysteine levels for Sample A and Sample B, from these Westmead results are:

  • Both samples showed significantly different trend
  • After an initial fall, Sample A increased to remain consistently above the limits
  • Sample B showed much less distinct initial increase that Sample A
  • Sample B reached a peak later than Sample A
  • Sample B fell rapidly after re-commencing oral B12
  • Last four A samples were destroyed by Mater Pathology.
Chart C26

 

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