THE VITAMIN B12 AND FOLATE PATHOLOGY INVESTIGATION
THE INVESTIGATION OF ERRORS IN PATHOLOGY TESTS
FOR VITAMIN B12 AND FOLATE DEFICIENCY
BY MEANS OF MEDICAL EXPERIMENTS
THE METHYLMALONIC ACID INVESTIGATION
THE MMA EXPERIMENT
Summary
Method
Observations
Results - Notes
Results - Series 1
Conclusions
Diagnostic Utility

In addition to very significant analytical error, the Mater Pathology reports quoted MMA cut-off levels higher than any other lab. The original cut-off, of 1.0 umol/L, could cause a significant number of cases of vitamin B12 deficiency to be missed.

Having regard to the results of my investigation, set out in this web site, in my opinion, the Mater Pathology quoted cut-off for MMA cannot be relied on for the diagnosis or monitoring of vitamin B12 deficiency.

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